Isolation of two cytotoxic diterpenes from the fern Pteris multifida.

نویسندگان

  • H J Woerdenbag
  • L R Lutke
  • R Bos
  • J F Stevens
  • R Hulst
  • W H Kruizinga
  • Y P Zhu
  • E T Elema
  • H Hendriks
  • W van Uden
  • N Pras
چکیده

From aerial parts of the fern Pteris multifida Poir. (Polypodiaceae) two diterpenes, entkaurane-2 beta, 16 alpha-diol and ent-kaur-16-ene-2 beta, 15 alpha-diol, were isolated by repeated column chromatography using silica gel and silica gel impregnated with silver nitrate. The structures were confirmed by spectroscopic methods. Both compounds showed a moderate cytotoxicity to Ehrlich ascites tumour cells.

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عنوان ژورنال:
  • Zeitschrift fur Naturforschung. C, Journal of biosciences

دوره 51 9-10  شماره 

صفحات  -

تاریخ انتشار 1996